For once, Apple seems to be taking a page out of Microsoft's book by breaking iPod compatibility with 3rd-party applications. Most iPod owners I know hate the iTunes software, and regularly use other programs to avoid dealing with the sluggish and buggy iTunes. This brings up an eerie similarity to Microsoft's decision to use a new, proprietary sync standard for Zune in place of their old, proprietary standard for PlaysForSure devices.
Re-enabling 3rd-party iPod sync isn't as simple as tweaking a few lines of code in the affected applications. It seems Apple has locked the iPod's iTunesDB file (what stores the song lists and settings of the iPod) with a SHA1 hash signature (the same type used to secure the Zune's firmware).
Even the New York Times, in a strikingly pro-Apple piece, brought up the hypocrisy of Steve Jobs' January Macworld announcement decrying the Zune a failure after gaining only 2% of the digital audio player market—a mere two months after its release. "Start your photocopiers", indeed.