Depending upon destination, the main pocket would carry either my old Dell notebook OR a Dell Mini (on end) along with a paperback Bible. (Per description, should fit with 1" to spare....)
With either, add a trackball, power cord & charger, perhaps a Cat 5 cable (some hotels don't do wireless in all rooms yet...), an Axim X30 with extra battery, paper, pens, & a nice supply of wintergreen mints

, and you are nicely set up.